Tamblyn's addition to the cast was confirmed on August 7, 2013, and she made her first appearance in the season premiere. It had been announced on that a female character was to be added to the show and that producers were looking for a woman to play the part. In his absence, the series introduced Amber Tamblyn, who portrays Jenny, the illegitimate, lesbian daughter of Charlie Harper. Jones was originally downgraded to a recurring cast member this season while he attended college however, on March 18, 2013, Jones officially confirmed that he would not return for season 11. He would return the following season as a guest star in the show's final episode. Jones, who portrayed Jake Harper during the first ten seasons, in any capacity. This season is also the first and only season not to feature Angus T. Tamblyn was promoted to series regular on October 2, 2013. This season marks another major change in the series as Amber Tamblyn joins the cast as Jenny, Charlie's illegitimate daughter.

The eleventh season of Two and a Half Men premiered on CBS on September 26, 2013, and ended on May 8, 2014.

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